Efficiency and Safety of Human Reproductive Cell/Tissue Vitrification

Potential importance of vitrification in reproductive medicine.

As early as 1985, ice-free cryopreservation of mouse embryos at -196 degrees C by vitrification was reported in an attempted alternative approach to cryostorage. Since then, vitrification techniques have entered more and more the mainstream of animal reproduction as an alternative cryopreservation method to traditional slow-cooling/rapid-thaw protocols. In addition, the last few years have seen...

Nuclear waste vitrification efficiency: Cold cap reactions

a r t i c l e i n f o Batch melting takes place within the cold cap, i.e., a batch layer floating on the surface of molten glass in a glass-melting furnace. The conversion of batch to glass consists of various chemical reactions, phase transitions , and diffusion-controlled processes. This study introduces a one-dimensional (1D) mathematical model of the cold cap that describes the batch-to-gla...

Efficiency of safety barriers facing human errors

this paper proposes a new approach for assessing the efficiency of barriers and of barrier removals. Facing defences in depth organized by physical barriers implemented on the human-machine system or by immaterial barriers such as procedures to be applied, barrier removal is an intentional human error and consists in not respecting the existing barriers of the human-machine system. An approach ...

Safety Assessment of cryIAc for human, animals and environment

Risk assessment of a transgene is one of the key steps in genetic transformation. Hence, in order to use cryIAc gene for production of transgenic plants, a library and in-silico research was performed to confirm safety of the gene for human comsumption, animal feed and environment. In the first step, the molecular mechanism of action of the CryIAc protein and its specific receptors in the midgu...

Reproductive efficiency of human oocytes fertilized in vitro